Written by Jaime Abstract It was hypothesized that the reaction substrates and conditions would be a viable option for industrial and large scale synthesis of the target coumarin product. Ethyl phenylpropiolate was synthesized from phenylacetylene and ethylchloroformate. It was then combined with sesamol, in the presence of palladium acetate as a catalyst, to synthesize 6,7-mehtylenedioxy-4-phenylcoumarin. Introduction Coumarins are naturally occurring molecules that are found in plants that have numerous uses in the medical field because of its biological activity. The […]
