Biginelli Reaction By: Mark Roberto Postlab Questions Questions 1, 3, and 4 on separate paper. 2) 3,4-dihydropyrimidones are calcium channel blockers. This means that they block calcium ion flow through membrane channels in cells.[1] Results Using the Bignelli reaction, acetoacetamide, benzaldehyde, and urea were reacted in a 1:1:1 ratio to synthesize a 3,4-dihydropyrimidinone that will be called “product”. The limiting reagent was determined to be the acetoacetamide, which was 3.936 mM (0.3979g/101.10g/mol). For the urea, 3.996 mM were used […]
