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Tag : Esterification

Synthesis of Aspirin and Flavoring Esters

Synthesis of Aspirin and Flavoring Esters By: Leah Warkel and Matt Glattfelder Introduction An ester is an organic compound that is formed by combining a carboxylic acid and an alcohol.1 It has the general formula R-CO-OR’.2 If an alcohol undergoes a condensation reaction, an ester is formed. This is reversible however, so if an ester undergoes hydrolysis, an alcohol is formed.1 A condensation reaction is when a molecule combines with another molecule to produce a larger molecule and a smaller […]

Esterification of Benzocaine

Esterification of Benzocaine By: Nick Makowski and Monica Schaeffer Purpose: To practice the techniques of refluxing and vacuum filtration to perform an esterification reaction to create benzocaine from p-aminobenzoic acid Chemical Structures/Reactions/Mechanisms: Results: Physical Appearances- After ethanol and sulfuric acid added to p-aminobenzoic acid, solution became clumpy and then turned into a white foam After refluxing, solution became more solid Upon filtration, white benzocaine crystals formed Mass of Substances- p-aminobenzoic acid: 1.201g benzocaine: 0.368g Na2CO3: 11mL Melting Point- Known= 88-90 […]