By: Colleen Tuttle Abstract Chemical kinetics determines the overall order of the reaction, as well as the order of each of the reactants. In this lab, a series of reactions, with slight variations in concentrations were completed so the overall order of the reaction could be determined. Introduction Chemical kinetics is the study of determining the rate of a reaction under certain conditions. The rate law of a reaction uses the kinetic information of the concentrations at various […]
Using the Grignard Reaction to Prepare Triphenylmethanol By: Alexis Huddleston Abstract Grignard reagents are considered to be organometallic reagents and are therefore usually strong Lewis bases and function as good nucleophiles. In anhydrous reaction conditions, the formation of Grignard reagents can occur when the reagent is reacted with an organic halide. As demonstrated in the lab, phenylmagnesium bromide, an organic halide, can react with methyl benzoate along with the Grignard reagent to produce triphenylmethanol. Since Grignard reagents are extremely […]
By: Robert Burns Abstract: The purpose of this experiment was to successfully synthesize dihydrojasmone through a series of synthetic steps starting from levulinic acid. Then, using 1,1’-carbonyldiimidazole (CDI), the acid was turned into a Weinreb amide. After a simple conversion of the carbonyl group to a ketal, the amide was reacted with hexyl magnesium bromide to give the 1,4 diketone. The diketone was then refluxed under basic conditions to afford dihydrojasmone as a light brown liquid (0.06g, 28.0%). All products […]
A Practical Use for Paper Chromatography By: Matthew Schweitzer Introduction: Chromatography is a major operation used in many different operations in chemistry. Chromatography is a method of separation in which the components of a substance are separated and distributed between two phases which are the mobile phases and stationary phase.1 There are different methods of chromatography. These include column chromatography, planar chromatography (paper chromatography), development chromatography, elution chromatography, retention chromatography, gas chromatography, and liquid chromatography.2 The experiment that was conducted […]
Summary Report II This report contains information from labs three and four. These labs were the continuation of previous weeks and in process of obtaining the same overall goal. The semester long lab is broken down into important milestones that must be accomplished to move to the next step. The milestones are explained in the next paragraph. The semester long project as previously stated in the prior summary may have been unclear. The purpose of this semester long lab is […]
By: Kristen Powell, Morgan Sanders, Robert Walker This is a Laboratory Journal of Organic Chemistry Note for synthesis reaction data obtained in the Organic Chemistry Laboratory—All information was experimentally conducted. This article should be used as a reference when conducting your own synthesis reactions. Three reactions containing alcohol groups, on primary and secondary carbons reacting with halide groups have been the topic of investigation through experimental testing. The substitution pathway varied between reactions due to the different structures. Variables such as […]
